We also estimated heritability partitioned by chromosomes and MAF bins and compared the results with those from Davis et al. (5). Following Davis, we created six MAF bins: 0.01–0.05, 0.05–0.1, 0.1–0.2, 0.2–0.3, 0.3–0.4, and 0.4–0.5. For each bin, we computed a GRM, and then additive genetic variance attributed to each subset was jointly estimated with multiple GRM (using --mgrm in GCTA). This allows for the effects of LD to be partitioned by the REML.
