With regard to psychiatric disorders, the 3 familial factors did not differ significantly in their association with a lifetime diagnosis of GAD, although when examined individually, regression coefficients were significant for rule breaking and overt aggression but not covert delinquency. However, the 3 factors differed significantly in their association with antisocial personality disorder symptoms, with the effect size especially strong for overt aggression, slightly weaker for rule breaking, and much weaker (albeit significant) for covert delinquency. The 3 familial factors did not differ significantly in their association with cocaine and alcohol dependence, although the regression coefficient appeared weakest in each case for covert aggression. Interestingly, whereas cocaine dependence was associated most strongly with overt aggression, alcohol dependence was associated most strongly with rule breaking.