be a shared environment effect, a non-shared environment effect, or even another phenotype. To avoid confusion with the GxE described above, and to incorporate the concept of a moderator variable that may or may not be truly environmental, we will use the term GxM to refer to contextual moderation of genetic risk, where M refers to the moderating variable. Similarly, CxM refers to contextual moderation of shared environmental risk, and ExM refers to contextual moderation of non-shared environmental risks.