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Chunk #4 — 1. Introduction — 1.1 Moderation of genetic risk

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Perceived peer delinquency and the genetic predisposition for substance dependence vulnerability.
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be a shared environment effect, a non-shared environment effect, or even another phenotype. To avoid confusion with the GxE described above, and to incorporate the concept of a moderator variable that may or may not be truly environmental, we will use the term GxM to refer to contextual moderation of genetic risk, where M refers to the moderating variable. Similarly, CxM refers to contextual moderation of shared environmental risk, and ExM refers to contextual moderation of non-shared environmental risks.