The sample size of people included in at least one analysis consisted of 443,693 individuals (maximum sample size per analysis N = 362,018). Slightly more than half of the participants (54%) were female (25Up: 61%, S4S: 58%, NTR: 62%, UKB: 54%), and age ranged from 18 to 94 with a weighted mean age of 38 years (25Up: M = 30.1, SD = 4.3; S4S: M = 20.7, SD = 1.5; NTR: M = 44.8, SD = 16.9; UKB: M = 54.7, SD = 8.0). Furthermore, most participants had a moderate (49%) or high (33%) level of education (largest group 25Up: 41.7% moderately high, S4S: 77.5% high, NTR: 45.7% high, UKB: 32.4% high education).
