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Chunk #21 — RESULTS — Structural and evolutionary characteristics of XLMR genes

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A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.
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The known biological functions of proteins encoded by genes involved in XLMR are diverse. To explore further the attributes of these genes and their encoded proteins, we compared features of currently identified genes associated with XLMR (80 genes) to X-chromosome genes associated with disease phenotypes that do not include cognitive impairment (61 genes) and X-chromosome genes that have not yet been associated with a mendelian disease (608 genes).