showed resistance to cocaine reinforcement and exhibited increased acetylation of histone H3 and BDNF mRNA and protein expression in the medial prefrontal cortex (Vassoler, White, Schmidt, Sadri-Vakili, & Pierce, 2013). Overall, these examples provide evidence that an epigenetic state, which maintains a changed behavior of a system in a stable manner, can be heritable and co-exist with our genome for subsequent generations.
