a 6:2:1 ratio. Our results are notable for two reasons as we describe significant ethanol potentiation in GABAA receptors lacking α4/6 and/or δ subunits and we observed potentiation or inhibition by ethanol which was dependent on subunit ratio. The specificity of the response, i.e. potentiation vs. inhibition, is of interest because it demonstrates that changes in subunit abundance can alter response to ethanol.
