In summary, our results demonstrate that the majority of inherited liability for OCD in Sweden traces to common genetic variation. Moreover, our results show that the distribution of risk as a function of allele frequency is consistent with expectations, indicating that balancing selection, or other more complex evolutionary forces, are not strongly at play in OCD. Furthermore, our results indicate that risk for OCD is distributed across the genome as expected and that results presented here and in prior studies are consistent with the infinitesimal model for OCD. Finally, our results support the continued study of rare variation, both inherited and de novo, in OCD risk.
