Cigarette smoking is common in both industrialized and developing countries. In the U.S., over 43 million people use tobacco, and worldwide, there are over 1 billion tobacco users [1-2]. Though smoking is on the decline in developed countries because of effective anti-smoking campaigns, in developing countries, tobacco use continues to increase. Despite reductions in current smoking among the U.S. population over the past four decades, each year over 400,000 people die from tobacco-related illnesses [1], and smoking remains the greatest contributor to preventable mortality [3]. Worldwide, the annual death toll from tobacco use is 5 million people, and with increasing tobacco use in developing countries, it is predicted that the worldwide death toll will rise to 8 million per year by 2030 [2].
