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Chunk #26 — Functional maturation of motivation control

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Functional brain imaging across development.
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While developmental activation changes in OFC and ACC have been inconsistent during reward-related tasks, studies seem to converge, however, in that ventral striatum is more activated in adolescents than adults during reward outcome, suggesting heightened sensitivity to rewards in adolescence that could potentially explain higher risk-taking behaviours [65, 66, 68]. Recent studies highlight non-linear developmental changes in the activation of motivation control regions. Thus, during a decision-making task, a peak was observed in adolescence (12–17 years) relative to childhood (8–10 years) and adulthood (19–26 years) for vmPFC activation during the choice phase and a peak in VS during the outcome phase of the task, despite comparable task performance [69]. In line with this are findings that during happy No-Go trials, known to elicit approach behaviour, adolescents (13–17 years), relative to both children (6–12 years) and adults (18–29 years) made more commission errors and showed heightened activation in ventral striatum that was not observed during neutral No-Go trials and that survived correction for performance differences [70]. Overall, the findings suggest that development of motivation control is associated with non-linear changes, where