Samples from neuronal differentiation of 2 additional BPD and 2 control iPSC lines, were also analyzed by qRT-PCR. These lines were derived from fibroblasts from the same Old Amish population isolate (Coriell Catalog ID: GM05926, GM05934, GM05904, GM05930) using the methods described above. These cases had the same diagnostic reliability, and for the BPD patients, lithium responsiveness. Inclusion of data from these samples did not change the overall expression profiles of candidate genes assessed (data not shown).