areas. Cortico-limbic pathways should be considered in future work examining SG differences in the neuroimaging of AUD. The degree of mixed results on SG-based differences in brain function and morphometry in AUD may be a result of the low rates of female enrollment in AUD neuroimaging studies and the low rates of AUD neuroimaging studies that analyze data by SG (see Table 1). It would also benefit the state of field by including quantitative values within original research publications to identify the magnitude of SG differences in the neuroimaging of alcohol use. The findings of this review critically underscore the need to include more female participants in neuroimaging studies, possibly by over-recruiting women and/or conducting stratified analyses, to further elucidate SG differences in neural mechanisms underlying AUD and to ultimately improve SG-appropriate pharmacotherapeutic treatment of AUD.
