Chunk #43 — Findings — Improvements in PLINK 1.9 — Other noteworthy algorithms — Coordinate-descent LASSO

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Second-generation PLINK: rising to the challenge of larger and richer datasets.

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PLINK 1.9 includes a basic coordinate-descent LASSO implementation [27] (–lasso), which can be useful for phenotypic prediction and related applications. See Vattikuti et al. for discussion of its theoretical properties [28].