Chunk #22 — Results — Polygenic prediction in the Partners Biobank

Source

Polygenic prediction via Bayesian regression and continuous shrinkage priors.

Embedded

yes

Text

Overall, using the Partners HealthCare Biobank data as an in-sample LD reference (N = 19,136) instead of the 1KG reference panel slightly increased the prediction accuracy but the improvement was marginal (Supplementary Fig. 6 and Supplementary Data 3).