Mood disorders affect 10–20% of the global population across their lifetime, ranging from brief, mild episodes to severe, incapacitating conditions that markedly impact lives (1–4). Major depressive disorder and bipolar disorder are the most common forms and have been grouped together since the third edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III) (5). Although given dedicated chapters in DSM5, they remain grouped as mood disorders in the International Classification of Disorders (ICD11) (6, 7).
