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Chunk #1 — Introduction

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Sex differences in the genetic architecture of obsessive-compulsive disorder.
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Nestadt, Grados, and Samuels 2010). Compared to females, males with OCD report more religious, sexual, and symmetry symptoms, more alcohol dependence, and lower rates of marriage and employment. Females with OCD are more likely to be married, report more sexual abuse during childhood, often report exacerbation of symptoms in the premenstrual/menstrual period, during/shortly after pregnancy, with menopause, and tend to have more contamination and cleaning compulsions, as well as eating disorders, reviewed in Mathis et al (Mathis et al. 2011).