loci. Denote a particular set of alleles such as this by Sk. The composite sample frequency of this four loci allele set is where H(Gi) is the number of single-locus heterozygotes in the multilocus genotype Gi of the ith individual, i=1, … ,n, and I(·) is the indicator function that is equal to 1 if the ith individual has alleles (Sk), and 0 otherwise.
