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Chunk #20 — Discussion — Historical candidate genes for schizophrenia in light of current empirical results

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Evaluating historical candidate genes for schizophrenia.
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Third, even before the current generation of large genomic studies for schizophrenia, it was reassuring to note that candidate gene meta-analyses by other authors (Table S2) 26–41 and our SZGene meta-analyses (Table 2) were converging on the null. This is important because the candidate gene literature for common variation in schizophrenia is often believed to be replete with false positive claims: this generality is not supported by meta-analysis.