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Chunk #37 — PRS in treatment choice

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Polygenic risk scores: from research tools to clinical instruments.
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and time to recovery. An important perspective in genetic testing for treatment response is in identifying patients who are unlikely to respond to a specific drug, as Gibson highlights [75, 76]. This could reduce the time taken by clinicians to find efficacious treatment, improve treatment response, and prevent treatment-related adverse effects, which is cost-effective for both the patient and the healthcare system. When the choice of treatment is not dictated by different effectiveness, but from personal experience, preference, or intuition on a trial-and-error basis, PRS can potentially give some quantifiable information to be considered along other lines of evidence.