ages were not significant (women: SLE × ONS17: b = 0.05, SE = 0.05; SLE × ONS14: b = 0.07, SE = 0.08; men: SLE × ONS17: b = 0.001, SE = 0.07; SLE × ONS14: b = 0.08, SE = 0.06; Model 5) and provided little additional explained variance in PYDD (Model 5 vs. 4: ΔR2 = 0.21% in women, 0.04% in men). Figure 2A,B shows the expected values of PYDD for women and men by onset age group based on the estimates from Models F5 and M5, respectively. The evidence of interactions is weak but is in a pattern consistent with that reported by Dawson and colleagues (2007): the earliest onset drinkers with most SLE reported the greatest PYDD.
