Chunk #20 — Results — Interaction with AMPARs converts CNIH-2 into a surface membrane protein

Source

AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling.

Embedded

yes

Text

Taken together, these data indicate that the interaction with AMPARs has converted CNIH-2 from a sole cargo exporter promoting anterograde trafficking into a surface membrane protein modifying the signaling of the receptors.