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Chunk #2 — RESULTS

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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
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We analyzed genome-wide single nucleotide polymorphism (SNP) data for eight neuropsychiatric disorders using a combined sample of 232,964 cases and 494,162 controls (Table 1; Table S1). The eight disorders included AN (Duncan et al., 2017) ASD (Grove et al., 2019a), ADHD (Demontis et al., 2019), BIP (Stahl et al., 2019), MD (Wray et al., 2018), OCD (International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS), 2018), TS (Yu et al., 2019), and SCZ (Schizophrenia Working Group of the Psychiatric Genomics, 2014). All study participants were of self-identified European ancestry, which was supported by principal component analysis of genome-wide data.