Chunk #33 — Results — Survival mixture analysis

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The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

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The size of the sample containing subjects with or without first use and available genetic data was N ≈ 775 for the five phenotypes. The results of the model comparisons are presented first together with a conceptual interpretation of the best fitting model for each phenotype in terms of risk of first use over time. This is followed by the results concerning genetic effects.