We obtained hippocampal samples from the adult offspring of rat mothers that differed in the frequency of pup licking/grooming in the first week of life (i.e. High vs Low LG adult offspring) and performed an analysis of DNA methylation, H3K9 acetylation and gene expression of a contiguous 7 million base pair region of rat chromosome 18 containing the NR3C1 gene at 100 bp spacing. To our knowledge, these epigenetic and transcriptional profiles constitute the first tiling microarray data set exploring the relationship between epigenetic modifications and RNA expression in both protein coding and non-coding regions across a chromosomal locus in the mammalian brain.
