MANOVA among the 3 Caine groups and across the 6 functional domains was significant (F(2,118)=10.30, p<.0001). Differences among the Caine groups were observed for Production (F(2,83)=4.87, p=.01), Immediate Memory (F(2,82)=7.40, p=.001), Delayed Memory (F(2,82)=6.98, p=.002), and Upper Limb Motor (F(2,83)=5.08, p=.008) composite scores. Caine groups did not differ on Attention/Working Memory (F(2,80)=1.36, p=.26) or Visuospatial (F(2,83)=1.41, p=.25) composite scores (Figure 2). Follow-up analyses indicated that for the 4 composites with group differences, Caine 2+ demonstrated the most severe deficits, scoring lower than Caine 0 or Caine 1.
