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Chunk #2 — Introduction

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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
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Similarly, there has been no method to systematically determine the cellular effects of chemical compounds. For example, it would be desirable to be able to query a functional look-up table to discover unexpected activities of a compound – such activities often being discovered only late in the drug development process, resulting in side effects that limit clinical use.