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Chunk #26 — Discussion

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Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.
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and frontal theta activity during stimulus processing (Gallinat and others 2006). The results suggest a functional coupling between the frontal cortex and hippocampal region during stimulus processing and support the idea of the hippocampus as a neural rhythm generator driven by glutamatergic neurotransmission (Gallinat and others 2006). It is possible that modulation of glutamate release has a role in inhibiting cortical and sub-cortical glutamatergic sub-systems which are irrelevant to the processing of the target condition and thereby facilitating the information processing in the relevant sub-systems.