Finally, genetic analyses have consistently benefitted from larger sample sizes. Here, we report initial progress toward the identification of genetic factors influencing alcohol sensitivity, but these efforts must be bolstered by combining data across samples to increase statistical power. Given its ease of use and evidence of validity, the SRE represents a potentially powerful tool to employ to that end. However, the SRE does not capture all dimensions of alcohol sensitivity, and the subjective nature of the measure introduces uncertainty into analyses that are sensitive to measurement error, as is the case for most complex behavioral traits. Studies of more objective measures, such as body sway or motor coordination, would complement studies employing the SRE.
