Only nicotine dependence was associated with rs1409568, and in CATS alone (p = .003) – adding nicotine dependence as a covariate to the CATS analysis did not greatly alter the significance of rs1409568 (p = 5.51E-8; Supplemental Table S10). Alcohol dependence was not associated with rs1409568 in any individual study, although the meta-analytic p-value was less than 0.05.
