Participants were recruited from two sources. Some came via the public security system because they had been referred to compulsory rehabilitation centers (CRCs), which are the major treatment modality for drug users and responsible for detoxifying arrested drug users. Others came via the healthcare system because they were attendees of voluntary rehabilitation centers (VRCs), which are designated centers for treating substance addiction. Both the compulsory and voluntary settings are restrictive environments with structural and regulatory procedures to control or eliminate access to drugs. The relapse rate of drug users in the both CRCs and VRCs was at least 80% and many of them continue in a cycle of relapse and compulsory or voluntary rehabilitation. The participants came from urban and from rural backgrounds. We avoided recruiting the same participant at different times and from different sources by screening their name, birthday and personal identification numbers. Consecutive current MA-dependent males were recruited from Hunan Bainihu and Xinkaipu CRCs and from Hunan Kangda VRC between March 2013 and January 2014. Consecutive current heroin-dependent males were recruited from Xinkaipu and Baimalong CRCs and from the Hunan Second People’s Hospital VRC between March and October 2008.