When EUR and AFR results were meta-analyzed (n=143,965 subjects total), we identified two additional GWS loci, uncharacterized LOC105376602 (p= 4.63×10−08) on chromosome 11, and FGF14 (p= 9.86×10−09) on chromosome 13 (Supplementary Figure 5b and 5e). In addition, the associated region at CRHR1 increased in statistical significance to p=1.02×10−13. Comparing EUR results (Supplementary Figure 4a) with EUR-AFR meta-analysis (Figure 2c), we observed different lead variants on chromosome 17, but they both indicated CRHR1 as a credible gene responsible for the association observed. Results are summarized in Table 2 and more extensively in Supplementary Table 3.
