Interhemispheric functional connectivity examined synchronicity of BOLD signal fluctuations of bilateral regions over time. This analysis utilized the BOLD data extracted from the ROIs from each participant. Averaged left and right BOLD fluctuations from each ROI across 124 time points (excluded first four frames) were tested for significant associations using a Pearson correlation coefficient. The Fisher’s Z-transformation was applied to the correlation coefficients to allow for group comparisons between patient and normal controls. Between groups t-tests were used to detect significant differences in degree of interhemispheric connectedness between the respective groups for each ROI. Amplitude of BOLD fluctuation was inspected and were not determined to be statistically different between groups.
