National Institutes of Health (grant T32 HG000046 to S.J.D.); Institute Development Award to the Center for Applied Genomics from the Children's Hospital of Philadelphia (H.H.); National Institutes of Health (grant R01 MH604687 to M.B.); NARSAD distinguished Investigator Award (M.B.); National Institutes of Health (grant R01 CA124709 to J.M.M.); the Giulio D’Angio Endowed Chair and Alex's Lemonade Stand Foundation (J.M.M.). Funding for open access charge: R01 CA124709.