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Chunk #9 — Results — Stage 2 Validation

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Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
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We focused on rs1659258 as a new locus for independent validation in the non-overlapping cohorts that are part of the GIANT consortium data. Results are displayed in Table 2, with evidence for replication at this locus in women (p = 0.006) but not men (p = 0.24) for BMI. Similar results were observed for waist circumference.