This review is the first to summarize gene variants potentially related to the alcohol response while emphasizing the diversity of paradigms evaluating alcohol sensitivity. There is no single best approach for evaluating alcohol sensitivity, and the existing variety of methods has the benefit of describing multiple aspects of the alcohol response. However, the information offered above highlights the complexities among the various measures of alcohol responses, and it might be important to consider differences in research methods before combining results from different approaches into a single meta-analysis or GWAS.
