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Chunk #21 — Systematic review of structural MRI literature — Overview of structural MRI studies

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The effect of alcohol consumption on the adolescent brain: A systematic review of MRI and fMRI studies of alcohol-using youth.
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Our review also revealed gender differences in several, but not all studies included herein (Fein et al., 2013; Medina et al., 2008; Squeglia et al., 2012b). Specifically, several studies showed that compared with non-AU females, AU females had greater brain volumes across several regions including the thalamus and putamen (Fein et al., 2013), as well as smaller brain volumes in regions including the PFC (Medina et al., 2008). We also observed thicker cortices for AU females in the left frontal regions including the frontal pole, pars orbitalis, medial orbital frontal gyrus and rostral anterior cingulate (Squeglia et al., 2012b).