Chunk #2 — Human GPCs may be transplanted to restore lost myelin

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Modeling cognition and disease using human glial chimeric mice.

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recovery of a large minority(Windrem et al. 2008). Indeed, whereas untreated shiverers invariably die by 20–21 weeks of age, a fraction of neonatally-engrafted mice achieved normal lifespans of over 2 years, suggesting the potential power of this approach towards remyelinating dysmyelinated brain tissue (Figure 1).