After finding that few significant diagnostic differences in substance use prior to hospitalization, we investigated the longitudinal patterns for the use of the two most commonly used substances, alcohol and cannabis, over the course of 1-year. As can be seen in Table 3, results of unconditional growth models revealed that the overall proportion of patients using alcohol and cannabis significantly decreased over 1-year. Equivalent proportions of patients reported using alcohol post-hospitalization across diagnostic groups; however, the proportion of schizophrenia-spectrum and depressed patients using cannabis declined at significantly greater rates over the course of the study compared to patients with bipolar disorders who used cannabis.