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Chunk #24 — 4. Discussion

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Test of association between GABRA2 (SNP rs279871) and adolescent conduct/alcohol use disorders utilizing a sample of clinic referred youth with serious substance and conduct problems, controls and available first degree relatives.
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In conclusion, while our results do not definitively support nor refute the previously reported association between GABRA2 and CD, they offer another important piece of information on this topic. Such work to define the genetic determinants of risk for CD is exceedingly important and may accumulate to offer hope for better understanding the etiology of CD and the development of more effective long-term treatments.