Scatter plots of the tag counts around genomic peak coordinates enable comparative visualization of experimentally observed peaks and allow the overlay of other annotations present at these genomic coordinates. (For example, the tag counts associated with PU.1 peaks at the genomic coordinates a, b and c in Figure 1B are indicated in Figure 1C). Unexpectedly, more than 80% of the PU.1 sites localized to promoters (TSS ± 500 bp, green data points in Figure 1C) exhibited similar occupancy levels in both cell types, while differentially bound sites were mostly located in distal regions. (Figure 1C and 1D).
