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Chunk #78 — STAR Methods — QUANTIFICATION AND STATISTICAL ANALYSIS — ICA based analysis and clustering

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Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain.
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loading for each Biological IC defined their own particular subcluster. To do this, we clustered the cells across a range of the parameters k (number of nearest neighbors used in SNN generation) and r (resolution parameter in SLM), inspected the resulting clusters for enrichment for specific ICs, and selected a specific pair of parameters k and r that maximized the 1:1 correspondence between IC and subcluster (Figure S2J,K).