“significant” markers, such as p-values ranging from .50 to very small values. At a minimum, significant associations between such risk scores based on clinical outcomes and endophenotypes attest to the construct validity of the endophenotype for the clinical outcome in question. Studies have begun to appear that relate risk scores derived from PGC, for instance, to psychophysiological measures, such as PPI (Hall et al., 2015; Roussos et al., 2015).
