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Chunk #44 — 4. DISCUSSION

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Parent, sibling and peer associations with subtypes of psychiatric and substance use disorder comorbidity in offspring.
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Childhood physical/sexual abuse was less strongly associated with the AUD class compared to its association with the AUD-MDD-ANX and SUD-CD classes. This agrees with evidence from previous research showing that comorbid depression, as compared to pure depression, is more strongly associated with childhood trauma (Hovens et al., 2010), and that stressful life events, inclusive but not specific to trauma, are more strongly associated with comorbid SUD and affective disorder as compared to pure SUD (de Graaf et al., 2004).