The following 12 traits had CNS enrichment at FDR<5% in either the multiple tissue analysis of gene expression or in the analysis of chromatin data above: schizophrenia, bipolar disorder, Tourette syndrome, epilepsy, generalized epilepsy, ADHD, migraine, depressive symptoms, BMI, smoking status, years of education, and neuroticism. The nervous system has been implicated, either with genetic evidence or non-genetic evidence, for each of these traits7,34,24,32,45,71–73.
