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Chunk #54 — Methods — Summary Statistic Datasets

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An atlas of genetic correlations across human diseases and traits.
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Genomic control (GC) correction at any stage biases the heritability and genetic covariance estimates downwards (see the Supplementary Note of [19]. The biases in the numerator and denominator of genetic correlation cancel exactly, so genetic correlation is not biased by GC correction. A majority of the studies analyzed in this paper used GC correction, so we do not report genetic covariance and heritability.