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Chunk #27 — Materials and Methods — Confirmation study population

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Genome-wide association scan in HIV-1-infected individuals identifying variants influencing disease course.
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The Genomics of Resistance to Immunodeficiency Virus (GRIV) cohort was established in France in 1995 to generate a large collection of DNA for genetic studies to identify host genes associated with either rapid progression (n = 85) or non-progression (n = 275) to AIDS. Further information on participants, genotyping, quality control and statistical analysis are described in Limou et al [18] and Le Clerc et al [20].