Table 2 summarizes the results from the 30 lowest p-values from the SNP main-effect model (Equation 2). These findings correspond to p-values of 0.0021 and lower. An R2-binning procedure (Carlson et al. 2004) was used to identify bins of highly correlated SNPs (all R2 of 0.80 or higher), and only the top results from each bin are listed. Results are similar to those presented in Saccone et al (Saccone et al. 2007), but some discrepancies were expected because of differences in model specification, analysis sample composition, and SNP inclusion criteria. They are presented here for comparison with the interaction model results, and will not be discussed in detail except in that context.
