Our empirical p-values were 0.32 and 0.71 for parental knowledge and peer deviance, respectively. This indicates that the SNPs contributing to our polygenic scores were not individually enriched for gene-environment interaction, and further suggests that the polygenic moderation effects that we observed occur at the aggregate genetic level rather than at the level of individual SNPs. Attempts to replicate these effects in other independent datasets are critical for better understanding the contributions of individual SNPs to the aggregate effects observed for polygenic scores.
