In response to the lack of randomized controlled trials examining an exercise-based intervention for bipolar patients, Sylvia and colleagues developed a 20-week cognitive-behavioral intervention for bipolar disorder consisting of three modules: nutrition, exercise, and wellness [28]. Over the course of treatment, participants showed improvements in exercise, nutritional habits, depressive symptoms, and overall functioning [28, 53]. This study provides preliminary data that exercise is acceptable, feasible, and associated with functional improvement of bipolar patients.
