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Chunk #18 — Discussion — 4q23

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A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
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In conclusion, this study has identified two novel variants robustly associated with UADT cancers, and independently replicated three variants previously identified. All five variants variants are positioned near genes that appear relevant to etiology of UADT cancers, although further work is needed to identify the causative allele and gene at these loci.